| Reaction Details |
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 | Report a problem with these data |
| Target | Large T antigen |
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| Ligand | BDBM60369 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents |
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| IC50 | 7700±n/a nM |
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| Citation |  PubChem, PC Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Large T antigen |
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| Name: | Large T antigen |
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| Synonyms: | LT | LT-AG | LT_SV40 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 81575.54 |
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| Organism: | Simian virus 40 |
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| Description: | P03070 |
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| Residue: | 708 |
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| Sequence: | MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYK
KMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADS
QHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYS
VTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDP
FSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFE
MCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQM
LTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKR
YWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGG
ESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEFSVPKTLQAR
FVKQIDFRAKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWK
ERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHE
TGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET
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| BDBM60369 |
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| n/a |
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| Name | BDBM60369 |
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| Synonyms: | (2Z)-2-(1H-benzimidazol-2-yl)-2-(1-methyl-2-pyridinylidene)acetonitrile | (2Z)-2-(1H-benzimidazol-2-yl)-2-(1-methyl-2-pyridylidene)acetonitrile | (2Z)-2-(1H-benzimidazol-2-yl)-2-(1-methylpyridin-2-ylidene)acetonitrile | (2Z)-2-(1H-benzimidazol-2-yl)-2-(1-methylpyridin-2-ylidene)ethanenitrile | MLS000055643 | SMR000060192 | cid_2998445 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H12N4 |
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| Mol. Mass. | 248.2826 |
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| SMILES | CN1C=CC=C\C1=C(/C#N)c1nc2ccccc2[nH]1 |c:2,4| |
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| Structure | 
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