| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Large T antigen |
|---|
| Ligand | BDBM50309563 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents |
|---|
| IC50 | 3710±n/a nM |
|---|
| Citation |  PubChem, PC Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Large T antigen |
|---|
| Name: | Large T antigen |
|---|
| Synonyms: | LT | LT-AG | LT_SV40 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 81575.54 |
|---|
| Organism: | Simian virus 40 |
|---|
| Description: | P03070 |
|---|
| Residue: | 708 |
|---|
| Sequence: | MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYK
KMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADS
QHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYS
VTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDP
FSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFE
MCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQM
LTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKR
YWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGG
ESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEFSVPKTLQAR
FVKQIDFRAKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWK
ERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHE
TGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET
|
|
|
|---|
| BDBM50309563 |
|---|
| n/a |
|---|
| Name | BDBM50309563 |
|---|
| Synonyms: | 2-(2-(3,4-dihydroxyphenyl)-2-oxoethylthio)-4-(methoxymethyl)-6-methylnicotinonitrile | CHEMBL598663 | cid_586278 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H16N2O4S |
|---|
| Mol. Mass. | 344.385 |
|---|
| SMILES | COCc1cc(C)nc(SCC(=O)c2ccc(O)c(O)c2)c1C#N |
|---|
| Structure | 
|
|---|
Search and Browse
