Ki Summary

Reaction Details

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Target

Regulator of G-protein signaling 4

Ligand

BDBM46590

Substrate/Competitor

n/a

Meas. Tech.

Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao for SAR compounds

1020±n/a nM

Citation

PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao for SAR compounds PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Regulator of G-protein signaling 4

Name:

Regulator of G-protein signaling 4

Synonyms:

RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4)

Type:

Enzyme

Mol. Mass.:

23263.51

Organism:

Homo sapiens (Human)

Description:

P49798

Residue:

205

Sequence:

MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWA
ESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFIS
VQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNP
SSCGAEKQKGAKSSADCASLVPQCA

BDBM46590

n/a

Name

BDBM46590

Synonyms:

4-[2-[(E)-(2,3-dihydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]hydrazinyl]-3-nitrobenzenesulfonamide | 4-[2-[(E)-[2,3-bis(oxidanyl)-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene]methyl]hydrazinyl]-3-nitro-benzenesulfonamide | 4-[N'-[(E)-(2,3-dihydroxy-4-keto-cyclohexa-2,5-dien-1-ylidene)methyl]hydrazino]-3-nitro-benzenesulfonamide | 4-[[(E)-(2,3-dihydroxy-4-oxo-1-cyclohexa-2,5-dienylidene)methyl]hydrazo]-3-nitrobenzenesulfonamide | MLS000759826 | SMR000369866 | cid_5982653

Type

Small organic molecule

Emp. Form.

C13H12N4O7S

Mol. Mass.

368.322

SMILES

NS(=O)(=O)c1ccc(N=[NH+]Cc2ccc([O-])c(O)c2O)c(c1)[N+]([O-])=O |w:8.7|

Structure