Ki Summary

Reaction Details

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Target

Regulator of G-protein signaling 4

Ligand

BDBM47747

Substrate/Competitor

n/a

Meas. Tech.

Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao for SAR compounds

8200±n/a nM

Citation

PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao for SAR compounds PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Regulator of G-protein signaling 4

Name:

Regulator of G-protein signaling 4

Synonyms:

RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4)

Type:

Enzyme

Mol. Mass.:

23263.51

Organism:

Homo sapiens (Human)

Description:

P49798

Residue:

205

Sequence:

MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWA
ESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFIS
VQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNP
SSCGAEKQKGAKSSADCASLVPQCA

BDBM47747

n/a

Name

BDBM47747

Synonyms:

4-[(E)-[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H-1,2,4-triazol-4-yl]iminomethyl]benzoic acid methyl ester | 4-[[3-[3-(diethylsulfamoyl)phenyl]-5-sulfanylidene-1H-1,2,4-triazol-4-yl]iminomethyl]benzoic acid methyl ester | 4-[[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H-1,2,4-triazol-4-yl]iminomethyl]benzoic acid methyl ester | MLS000408811 | SMR000243078 | cid_2387418 | methyl 4-[[3-[3-(diethylsulfamoyl)phenyl]-5-sulfanylidene-1H-1,2,4-triazol-4-yl]iminomethyl]benzoate

Type

Small organic molecule

Emp. Form.

C21H23N5O4S2

Mol. Mass.

473.568

SMILES

CCN(CC)S(=O)(=O)c1cccc(c1)-c1n[nH]c(=S)n1N=Cc1ccc(cc1)C(=O)OC |w:20.21|

Structure