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Targetregulator of G-protein signaling 4
LigandBDBM47747
Substrate/Competitorn/a
Meas. Tech.Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao for SAR compounds
Ki 8200±n/a nM
Citation PubChem PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao for SAR compounds PubChem Bioassay (2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
regulator of G-protein signaling 4
Name:Regulator of G-protein signaling 4 (RGS4)
Synonyms:RGP4 | RGS4
Type:Enzyme
Mol. Mass.:23263.51
Organism:Homo sapiens (Human)
Description:P49798
Residue:205
Sequence:
MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWA
ESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFIS
VQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNP
SSCGAEKQKGAKSSADCASLVPQCA
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  Blast E-value cutoff:
BDBM47747
n/a
NameBDBM47747
Synonyms:4-[(E)-[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H-1,2,4-triazol-4-yl]iminomethyl]benzoic acid methyl ester | 4-[[3-[3-(diethylsulfamoyl)phenyl]-5-sulfanylidene-1H-1,2,4-triazol-4-yl]iminomethyl]benzoic acid methyl ester | 4-[[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H-1,2,4-triazol-4-yl]iminomethyl]benzoic acid methyl ester | MLS000408811 | SMR000243078 | cid_2387418 | methyl 4-[[3-[3-(diethylsulfamoyl)phenyl]-5-sulfanylidene-1H-1,2,4-triazol-4-yl]iminomethyl]benzoate
TypeSmall organic molecule
Emp. Form.C21H23N5O4S2
Mol. Mass.473.568
SMILESCCN(CC)S(=O)(=O)c1cccc(c1)-c1n[nH]c(=S)n1N=Cc1ccc(cc1)C(=O)OC |w:20.21|
Structure
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