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TargetRegulator of G-protein signaling 16
LigandBDBM47734
Substrate/Competitorn/a
Meas. Tech.Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao for SAR Compounds
EC50 5224±204.8 nM
Citation PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao for SAR Compounds PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Regulator of G-protein signaling 16
Name:Regulator of G-protein signaling 16
Synonyms:RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:Enzyme Catalytic Domain
Mol. Mass.:22748.87
Organism:Homo sapiens (Human)
Description:gi_156416009
Residue:202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVL
GWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEE
FICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDL
AAQASAASATLSSCSLDEPSHT
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BDBM47734
n/a
NameBDBM47734
Synonyms:MLS000553854 | N-[(4-methylphenyl)-(5-nitro-8-oxidanyl-quinolin-7-yl)methyl]propanamide | N-[(8-Hydroxy-5-nitro-quinolin-7-yl)-p-tolyl-methyl]-propionamide | N-[(8-hydroxy-5-nitro-7-quinolinyl)-(4-methylphenyl)methyl]propanamide | N-[(8-hydroxy-5-nitro-7-quinolyl)-(p-tolyl)methyl]propionamide | N-[(8-hydroxy-5-nitroquinolin-7-yl)-(4-methylphenyl)methyl]propanamide | SMR000172089 | cid_2922056
TypeSmall organic molecule
Emp. Form.C20H19N3O4
Mol. Mass.365.3826
SMILESCCC(=O)NC(c1ccc(C)cc1)c1cc([N+]([O-])=O)c2cccnc2c1O
Structure
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