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TargetRegulator of G-protein signaling 16
LigandBDBM62218
Substrate/Competitorn/a
Meas. Tech.Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao for SAR Compounds
EC50 30000±0 nM
Citation PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao for SAR Compounds PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Regulator of G-protein signaling 16
Name:Regulator of G-protein signaling 16
Synonyms:RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:Enzyme Catalytic Domain
Mol. Mass.:22748.87
Organism:Homo sapiens (Human)
Description:gi_156416009
Residue:202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVL
GWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEE
FICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDL
AAQASAASATLSSCSLDEPSHT
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BDBM62218
n/a
NameBDBM62218
Synonyms:2,4-dimethyl-6-[2-[3-methyl-4-(3-methylphenyl)-1-piperazinyl]-2-oxoethyl]-1,6-naphthyridin-5-one | 2,4-dimethyl-6-[2-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]-2-oxidanylidene-ethyl]-1,6-naphthyridin-5-one | 2,4-dimethyl-6-[2-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]-2-oxoethyl]-1,6-naphthyridin-5-one | 6-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]-2,4-dimethyl-1,6-naphthyridin-5-one | KUC103673N | cid_44473129
TypeSmall organic molecule
Emp. Form.C24H28N4O2
Mol. Mass.404.5047
SMILESCC1CN(CCN1c1cccc(C)c1)C(=O)Cn1ccc2nc(C)cc(C)c2c1=O
Structure
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