Reaction Details |
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Target | Regulator of G-protein signaling 16 |
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Ligand | BDBM62218 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao for SAR Compounds |
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EC50 | 30000±0 nM |
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Citation | PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao for SAR Compounds PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Regulator of G-protein signaling 16 |
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Name: | Regulator of G-protein signaling 16 |
Synonyms: | RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 22748.87 |
Organism: | Homo sapiens (Human) |
Description: | gi_156416009 |
Residue: | 202 |
Sequence: | MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVL
GWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEE
FICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDL
AAQASAASATLSSCSLDEPSHT
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BDBM62218 |
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n/a |
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Name | BDBM62218 |
Synonyms: | 2,4-dimethyl-6-[2-[3-methyl-4-(3-methylphenyl)-1-piperazinyl]-2-oxoethyl]-1,6-naphthyridin-5-one | 2,4-dimethyl-6-[2-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]-2-oxidanylidene-ethyl]-1,6-naphthyridin-5-one | 2,4-dimethyl-6-[2-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]-2-oxoethyl]-1,6-naphthyridin-5-one | 6-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]-2,4-dimethyl-1,6-naphthyridin-5-one | KUC103673N | cid_44473129 |
Type | Small organic molecule |
Emp. Form. | C24H28N4O2 |
Mol. Mass. | 404.5047 |
SMILES | CC1CN(CCN1c1cccc(C)c1)C(=O)Cn1ccc2nc(C)cc(C)c2c1=O |
Structure |
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