| Reaction Details |
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 | Report a problem with these data |
| Target | Regulator of G-protein signaling 16 |
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| Ligand | BDBM62221 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao for SAR Compounds |
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| EC50 | 30000±0 nM |
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| Citation |  PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao for SAR Compounds PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Regulator of G-protein signaling 16 |
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| Name: | Regulator of G-protein signaling 16 |
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| Synonyms: | RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 22748.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_156416009 |
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| Residue: | 202 |
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| Sequence: | MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVL
GWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEE
FICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDL
AAQASAASATLSSCSLDEPSHT
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| BDBM62221 |
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| n/a |
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| Name | BDBM62221 |
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| Synonyms: | 2-(4,6-dimethylisoxazolo[5,4-b]pyridin-3-yl)oxy-1-[3-methyl-4-(m-tolyl)piperazino]ethanone | 2-[(4,6-dimethyl-3-isoxazolo[5,4-b]pyridinyl)oxy]-1-[3-methyl-4-(3-methylphenyl)-1-piperazinyl]ethanone | 2-[(4,6-dimethyl-[1,2]oxazolo[5,4-b]pyridin-3-yl)oxy]-1-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]ethanone | KUC103676N | cid_44473132 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H26N4O3 |
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| Mol. Mass. | 394.4668 |
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| SMILES | CC1CN(CCN1c1cccc(C)c1)C(=O)COc1noc2nc(C)cc(C)c12 |
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| Structure | 
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