Reaction Details |
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Target | Regulator of G-protein signaling 8 |
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Ligand | BDBM47719 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao for SAR Compounds |
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EC50 | 127±n/a nM |
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Citation | PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao for SAR Compounds PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Regulator of G-protein signaling 8 |
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Name: | Regulator of G-protein signaling 8 |
Synonyms: | RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8) |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 20925.80 |
Organism: | Homo sapiens (Human) |
Description: | gi_74355113 |
Residue: | 180 |
Sequence: | MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVL
LSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE
VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
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BDBM47719 |
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n/a |
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Name | BDBM47719 |
Synonyms: | (4-chlorodithiazol-5-ylidene)-(4-chloro-2-methyl-phenyl)amine | 4-chloranyl-N-(4-chloranyl-2-methyl-phenyl)-1,2,3-dithiazol-5-imine | 4-chloro-N-(4-chloro-2-methylphenyl)-5-dithiazolimine | 4-chloro-N-(4-chloro-2-methylphenyl)dithiazol-5-imine | 4-chloro-N-(4-chloro-5H-1,2,3-dithiazol-5-yliden)-2-methylaniline | MLS000539990 | SMR000125448 | cid_1471255 |
Type | Small organic molecule |
Emp. Form. | C9H6Cl2N2S2 |
Mol. Mass. | 277.193 |
SMILES | Cc1cc(Cl)ccc1\N=c1\ssnc1Cl |
Structure |
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