Reaction Details |
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Target | Regulator of G-protein signaling 8 |
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Ligand | BDBM47770 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao for SAR Compounds |
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EC50 | 701±n/a nM |
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Citation | PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao for SAR Compounds PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Regulator of G-protein signaling 8 |
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Name: | Regulator of G-protein signaling 8 |
Synonyms: | RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8) |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 20925.80 |
Organism: | Homo sapiens (Human) |
Description: | gi_74355113 |
Residue: | 180 |
Sequence: | MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVL
LSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE
VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
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BDBM47770 |
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n/a |
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Name | BDBM47770 |
Synonyms: | 4-[5-[(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]-2-furanyl]benzenesulfonamide | 4-[5-[(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]furan-2-yl]benzenesulfonamide | 4-[5-[(4,6-diketo-2,2-dimethyl-1,3-dioxan-5-ylidene)methyl]-2-furyl]benzenesulfonamide | 4-[5-[[2,2-dimethyl-4,6-bis(oxidanylidene)-1,3-dioxan-5-ylidene]methyl]furan-2-yl]benzenesulfonamide | MLS000703574 | SMR000273939 | cid_1154580 |
Type | Small organic molecule |
Emp. Form. | C17H15NO7S |
Mol. Mass. | 377.369 |
SMILES | [#6]C1([#6])[#8]-[#6](=O)\[#6](=[#6]/c2ccc(o2)-c2ccc(cc2)S([#7])(=O)=O)-[#6](=O)-[#8]1 |
Structure |
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