| Reaction Details |
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 | Report a problem with these data |
| Target | Regulator of G-protein signaling 8 |
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| Ligand | BDBM47735 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao for SAR Compounds |
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| Ki | 170±n/a nM |
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| Citation |  PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao for SAR Compounds PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Regulator of G-protein signaling 8 |
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| Name: | Regulator of G-protein signaling 8 |
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| Synonyms: | RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 20925.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_74355113 |
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| Residue: | 180 |
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| Sequence: | MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVL
LSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE
VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
|
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| BDBM47735 |
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| n/a |
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| Name | BDBM47735 |
|---|
| Synonyms: | 3-chloranyl-N-(3,3-dimethylbutan-2-yl)-6-nitro-1-benzothiophene-2-carboxamide | 3-chloro-6-nitro-N-(1,2,2-trimethylpropyl)-1-benzothiophene-2-carboxamide | 3-chloro-6-nitro-N-(1,2,2-trimethylpropyl)benzothiophene-2-carboxamide | 3-chloro-N-(3,3-dimethylbutan-2-yl)-6-nitro-1-benzothiophene-2-carboxamide | MLS000583265 | SMR000201101 | cid_2971539 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H17ClN2O3S |
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| Mol. Mass. | 340.825 |
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| SMILES | CC(NC(=O)c1sc2cc(ccc2c1Cl)[N+]([O-])=O)C(C)(C)C |
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| Structure | 
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