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TargetRegulator of G-protein signaling 8
LigandBDBM47734
Substrate/Competitorn/a
Meas. Tech.Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao for SAR Compounds
Ki 3590±n/a nM
Citation PubChem PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao for SAR Compounds PubChem Bioassay (2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Regulator of G-protein signaling 8
Name:Regulator of G-protein signaling 8
Synonyms:Regulator of G-protein signaling 8 (RGS8)
Type:Enzyme Catalytic Domain
Mol. Mass.:20925.80
Organism:Homo sapiens (Human)
Description:gi_74355113
Residue:180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVL
LSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE
VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
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  Blast E-value cutoff:
BDBM47734
n/a
NameBDBM47734
Synonyms:MLS000553854 | N-[(4-methylphenyl)-(5-nitro-8-oxidanyl-quinolin-7-yl)methyl]propanamide | N-[(8-Hydroxy-5-nitro-quinolin-7-yl)-p-tolyl-methyl]-propionamide | N-[(8-hydroxy-5-nitro-7-quinolinyl)-(4-methylphenyl)methyl]propanamide | N-[(8-hydroxy-5-nitro-7-quinolyl)-(p-tolyl)methyl]propionamide | N-[(8-hydroxy-5-nitroquinolin-7-yl)-(4-methylphenyl)methyl]propanamide | SMR000172089 | cid_2922056
TypeSmall organic molecule
Emp. Form.C20H19N3O4
Mol. Mass.365.3826
SMILESCCC(=O)NC(c1ccc(C)cc1)c1cc([N+]([O-])=O)c2cccnc2c1O
Structure
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