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TargetRegulator of G-protein signaling 8
LigandBDBM33090
Substrate/Competitorn/a
Meas. Tech.Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao for SAR Compounds
Ki 470±n/a nM
Citation PubChem PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao for SAR Compounds PubChem Bioassay (2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Regulator of G-protein signaling 8
Name:Regulator of G-protein signaling 8
Synonyms:Regulator of G-protein signaling 8 (RGS8)
Type:Enzyme Catalytic Domain
Mol. Mass.:20925.80
Organism:Homo sapiens (Human)
Description:gi_74355113
Residue:180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVL
LSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE
VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
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  Blast E-value cutoff:
BDBM33090
n/a
NameBDBM33090
Synonyms:(4E)-4-[[(2-ethylimino-4-methyl-1,3-thiazol-3-yl)amino]methylidene]-2,3-bis(oxidanyl)cyclohexa-2,5-dien-1-one | (4E)-4-[[(2-ethylimino-4-methyl-1,3-thiazol-3-yl)amino]methylidene]-2,3-dihydroxycyclohexa-2,5-dien-1-one | (4E)-4-[[(2-ethylimino-4-methyl-3-thiazolyl)amino]methylidene]-2,3-dihydroxy-1-cyclohexa-2,5-dienone | (4E)-4-[[(2-ethylimino-4-methyl-4-thiazolin-3-yl)amino]methylene]-2,3-dihydroxy-cyclohexa-2,5-dien-1-one | (4Z)-4-[[(2-ethylimino-4-methyl-4-thiazolin-3-yl)amino]methylene]-2,3-dihydroxy-cyclohexa-2,5-dien-1-one | MLS000564170 | SMR000151702 | cid_5825518
TypeSmall organic molecule
Emp. Form.C13H15N3O3S
Mol. Mass.293.342
SMILESCCN=c1scc(C)n1N=Cc1ccc(O)c(O)c1O |w:9.9,2.1|
Structure
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