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TargetRegulator of G-protein signaling 8
LigandBDBM62216
Substrate/Competitorn/a
Meas. Tech.Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao for SAR Compounds
Ki 2640±n/a nM
Citation PubChem PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao for SAR Compounds PubChem Bioassay (2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Regulator of G-protein signaling 8
Name:Regulator of G-protein signaling 8
Synonyms:Regulator of G-protein signaling 8 (RGS8)
Type:Enzyme Catalytic Domain
Mol. Mass.:20925.80
Organism:Homo sapiens (Human)
Description:gi_74355113
Residue:180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVL
LSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE
VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
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  Blast E-value cutoff:
BDBM62216
n/a
NameBDBM62216
Synonyms:2-(4,6-dimethylisothiazolo[5,4-b]pyridin-3-yl)oxy-1-[3-methyl-4-(m-tolyl)piperazino]ethanone | 2-[(4,6-dimethyl-3-isothiazolo[5,4-b]pyridinyl)oxy]-1-[3-methyl-4-(3-methylphenyl)-1-piperazinyl]ethanone | 2-[(4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-yl)oxy]-1-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]ethanone | KUC103347N | UNM-0000305811 | cid_25227363
TypeSmall organic molecule
Emp. Form.C22H26N4O2S
Mol. Mass.410.532
SMILESCC1CN(CCN1c1cccc(C)c1)C(=O)COc1nsc2nc(C)cc(C)c12
Structure
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