Ki Summary

Reaction Details

Report a problem with these data

Target

Regulator of G-protein signaling 19

Ligand

BDBM47770

Substrate/Competitor

n/a

Meas. Tech.

Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao for SAR Compounds

230±n/a nM

Citation

PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao for SAR Compounds PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Regulator of G-protein signaling 19

Name:

Regulator of G-protein signaling 19

Synonyms:

Type:

Enzyme Catalytic Domain

Mol. Mass.:

24631.38

Organism:

Homo sapiens (Human)

Description:

gi_86990435

Residue:

217

Sequence:

MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQ
ASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFW
LACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDA
QLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA

BDBM47770

n/a

Name

BDBM47770

Synonyms:

4-[5-[(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]-2-furanyl]benzenesulfonamide | 4-[5-[(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]furan-2-yl]benzenesulfonamide | 4-[5-[(4,6-diketo-2,2-dimethyl-1,3-dioxan-5-ylidene)methyl]-2-furyl]benzenesulfonamide | 4-[5-[[2,2-dimethyl-4,6-bis(oxidanylidene)-1,3-dioxan-5-ylidene]methyl]furan-2-yl]benzenesulfonamide | MLS000703574 | SMR000273939 | cid_1154580

Type

Small organic molecule

Emp. Form.

C17H15NO7S

Mol. Mass.

377.369

SMILES

[#6]C1([#6])[#8]-[#6](=O)\[#6](=[#6]/c2ccc(o2)-c2ccc(cc2)S([#7])(=O)=O)-[#6](=O)-[#8]1

Structure