Ki Summary

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Target

Epstein-Barr nuclear antigen 1

Ligand

BDBM62494

Substrate/Competitor

n/a

Meas. Tech.

Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1)

IC50

6659±n/a nM

Citation

PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Epstein-Barr nuclear antigen 1

Name:

Epstein-Barr nuclear antigen 1

Synonyms:

EBNA-1 protein | EBNA1 | EBNA1_EBVB9 | Epstein-Barr virus protease (EBV Pr)

Type:

Enzyme Catalytic Domain

Mol. Mass.:

56444.81

Organism:

Human herpesvirus 4

Description:

gi_23893623

Residue:

641

Sequence:

MSDEGPGTGPGNGLGEKGDTSGPEGSGGSGPQRRGGDNHGRGRGRGRGRGGGRPGAPGGS
GSGPRHRDGVRRPQKRPSCIGCKGTHGGTGAGAGAGGAGAGGAGAGGGAGAGGGAGGAGG
AGGAGAGGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGG
AGGAGAGGGAGGAGGAGAGGGAGAGGAGGAGGAGAGGAGAGGGAGGAGGAGAGGAGAGGA
GAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGGAGAGGGAGGAGAGGAGGAGAGGA
GGAGAGGAGGAGAGGGAGAGGAGAGGGGRGRGGSGGRGRGGSGGRGRGGSGGRRGRGRER
ARGGSRERARGRGRGRGEKRPRSPSSQSSSSGSPPRRPPPGRRPFFHPVGEADYFEYHQE
GGPDGEPDVPPGAIEQGPADDPGEGPSTGPRGQGDGGRRKKGGWFGKHRGQGGSNPKFEN
IAEGLRALLARSHVERTTDEGTWVAGVFVYGGSKTSLYNLRRGTALAIPQCRLTPLSRLP
FGMAPGPGPQPGPLRESIVCYFMVFLQTHIFAEVLKDAIKDLVMTKPAPTCNIRVTVCSF
DDGVDLPPWFPPMVEGAAAEGDDGDDGDEGGDGDEGEEGQE

BDBM62494

n/a

Name

BDBM62494

Synonyms:

1-(2-fluorophenyl)-3-(5-veratryl-1,3,4-thiadiazol-2-yl)urea | 1-[5-[(3,4-dimethoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]-3-(2-fluorophenyl)urea | MLS001183471 | SMR000502099 | cid_1335528

Type

Small organic molecule

Emp. Form.

C18H17FN4O3S

Mol. Mass.

388.416

SMILES

COc1ccc(Cc2nnc(NC(=O)Nc3ccccc3F)s2)cc1OC

Structure