| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein phosphatase |
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| Ligand | BDBM64538 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminesence Cell-Based Secondary Assay to Identify Inhibitors of Calcineurin |
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| EC50 | 180000±n/a nM |
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| Citation |  PubChem, PC Luminesence Cell-Based Secondary Assay to Identify Inhibitors of Calcineurin PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Serine/threonine-protein phosphatase |
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| Name: | Serine/threonine-protein phosphatase |
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| Synonyms: | calcineurin A1, putative | calmodulin-binding protein 1, putative | serine/threonine-protein phosphatase 2B catalytic subunit A1, putative |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 69558.03 |
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| Organism: | Candida dubliniensis CD36 |
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| Description: | gi_223640082 |
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| Residue: | 607 |
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| Sequence: | MSGNTVQRNTEQINNALNAIQHRRTTTGNDLNHTNQRIISQNSINDKDYTIYITDDGEKY
STVERAVKSVDPPVTFKPKDEQVFLSNGKPNHQFLKQHFIHEGRLHEHQAIQILKQATHL
LSKESNLLNVPAPVTICGDVHGQYYDLMKLFEVGGDPATTKYLFLGDYVDRGSFSIECLL
YLYSLKINYPDTFWMLRGNHECRHLTEYFTFKNECLHKYSEQLYEECLVSFNALPLAAIM
NEQFFCVHGGLSPQLTSLDSLRKLHRFREPPTKGLMCDLLWADPIEEYDEDNIDQEYVTN
VVRGCSFAFTYKAACKFLDKTKLLSVIRAHEAQNAGYRMYKRTKTMGFPSLLTMFSAPNY
LDSYNNKAAVLKYENNVMNIRQFNASPHPYWLPHFMDVFTWSLPFVGEKVTDMLVSILNV
CTEEELDEDLPFSESEIGVATKTTKTTTPVSPVSPKAHPPSTRITSPYKSTKLVESDNNP
NTNNDDSEMTLEEKKQALRNKIIAIGKMSRMFQVLREEQENVAHLKELNRGSLPKGSLLH
GVDGLKNTINSFEEAKAADRINEALPPSPEDIQRLKQEKNTRIRQQIENQEMSGPVFQRL
IRRLSQS
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| BDBM64538 |
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| n/a |
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| Name | BDBM64538 |
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| Synonyms: | MLS000030000 | N-(5-Ethyl-[1,3,4]thiadiazol-2-yl)-2-[4-(4-phenyl-thiazol-2-yl)-piperazin-1-yl]-acetamide | N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-[4-(4-phenyl-1,3-thiazol-2-yl)piperazin-1-yl]acetamide | N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-[4-(4-phenyl-1,3-thiazol-2-yl)piperazin-1-yl]ethanamide | N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-[4-(4-phenyl-2-thiazolyl)-1-piperazinyl]acetamide | N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-[4-(4-phenylthiazol-2-yl)piperazino]acetamide | SMR000007114 | cid_653565 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22N6OS2 |
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| Mol. Mass. | 414.548 |
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| SMILES | CCc1nnc(NC(=O)CN2CCN(CC2)c2nc(cs2)-c2ccccc2)s1 |
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| Structure | 
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