| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein phosphatase |
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| Ligand | BDBM64545 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminesence Cell-Based Secondary Assay to Identify Inhibitors of Calcineurin |
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| EC50 | 180000±n/a nM |
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| Citation |  PubChem, PC Luminesence Cell-Based Secondary Assay to Identify Inhibitors of Calcineurin PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Serine/threonine-protein phosphatase |
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| Name: | Serine/threonine-protein phosphatase |
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| Synonyms: | calcineurin A1, putative | calmodulin-binding protein 1, putative | serine/threonine-protein phosphatase 2B catalytic subunit A1, putative |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 69558.03 |
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| Organism: | Candida dubliniensis CD36 |
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| Description: | gi_223640082 |
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| Residue: | 607 |
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| Sequence: | MSGNTVQRNTEQINNALNAIQHRRTTTGNDLNHTNQRIISQNSINDKDYTIYITDDGEKY
STVERAVKSVDPPVTFKPKDEQVFLSNGKPNHQFLKQHFIHEGRLHEHQAIQILKQATHL
LSKESNLLNVPAPVTICGDVHGQYYDLMKLFEVGGDPATTKYLFLGDYVDRGSFSIECLL
YLYSLKINYPDTFWMLRGNHECRHLTEYFTFKNECLHKYSEQLYEECLVSFNALPLAAIM
NEQFFCVHGGLSPQLTSLDSLRKLHRFREPPTKGLMCDLLWADPIEEYDEDNIDQEYVTN
VVRGCSFAFTYKAACKFLDKTKLLSVIRAHEAQNAGYRMYKRTKTMGFPSLLTMFSAPNY
LDSYNNKAAVLKYENNVMNIRQFNASPHPYWLPHFMDVFTWSLPFVGEKVTDMLVSILNV
CTEEELDEDLPFSESEIGVATKTTKTTTPVSPVSPKAHPPSTRITSPYKSTKLVESDNNP
NTNNDDSEMTLEEKKQALRNKIIAIGKMSRMFQVLREEQENVAHLKELNRGSLPKGSLLH
GVDGLKNTINSFEEAKAADRINEALPPSPEDIQRLKQEKNTRIRQQIENQEMSGPVFQRL
IRRLSQS
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| BDBM64545 |
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| n/a |
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| Name | BDBM64545 |
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| Synonyms: | 3,5-dimethyl-1-phenyl-4-pyrazolecarboxylic acid [3-cyano-3-(1,3-dihydrobenzimidazol-2-ylidene)-2-oxopropyl] ester | 3,5-dimethyl-1-phenyl-pyrazole-4-carboxylic acid [3-cyano-3-(1,3-dihydrobenzimidazol-2-ylidene)-2-keto-propyl] ester | MLS000053776 | SMR000068223 | [3-cyano-3-(1,3-dihydrobenzimidazol-2-ylidene)-2-oxidanylidene-propyl] 3,5-dimethyl-1-phenyl-pyrazole-4-carboxylate | [3-cyano-3-(1,3-dihydrobenzimidazol-2-ylidene)-2-oxopropyl] 3,5-dimethyl-1-phenylpyrazole-4-carboxylate | cid_5742508 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H19N5O3 |
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| Mol. Mass. | 413.4287 |
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| SMILES | Cc1nn(c(C)c1C(=O)OCC(=O)C(C#N)c1nc2ccccc2[nH]1)-c1ccccc1 |
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| Structure | 
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