| Reaction Details |
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 | Report a problem with these data |
| Target | ATP-dependent molecular chaperone HSP82 |
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| Ligand | BDBM34573 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole |
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| EC50 | 750±1259 nM |
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| Citation |  PubChem, PC Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| ATP-dependent molecular chaperone HSP82 |
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| Name: | ATP-dependent molecular chaperone HSP82 |
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| Synonyms: | heat shock protein 90 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 80784.12 |
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| Organism: | Candida albicans |
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| Description: | gi_994798 |
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| Residue: | 707 |
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| Sequence: | MADAKVETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLE
SEPELFIRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTKSFMEALSAGADVSMI
GQFGVGFYSLFLVADHVQVISKHNDDEQYVWESNAGGKFTVTLDETNERLGRGTMLRLFL
KEDQLEYLEEKRIKEVVKKHSEFVAYPIQLVVTKEVEKEVPETEEEDKAAEEDDKKPKLE
EVKDEEDEKKEKKTKTVKEEVTETEELNKTKPLWTRNPSDITQDEYNAFYKSISNDWEDP
LAVKHFSVEGQLEFRAILFVPKRAPFDAFESKKKKNNIKLYVRRVFITDDAEELIPEWLS
FIKGVVDSEDLPLNLSREMLQQNKILKVIRKNIVKKMIETFNEISEDQEQFNQFYTAFSK
NIKLGIHEDAQNRQSLAKLLRFYSTKSSEEMTSLSDYVTRMPEHQKNIYYITGESIKAVE
KSPFLDALKAKNFEVLFMVDPIDEYAMTQLKEFEDKKLVDITKDFELEESDEEKAAREKE
IKEYEPLTKALKDILGDQVEKVVVSYKLVDAPAAIRTGQFGWSANMERIMKAQALRDTTM
SSYMSSKKTFEISPSSPIIKELKKKVETDGAEDKTVKDLTTLLFDTALLTSGFTLDEPSN
FAHRINRLIALGLNIDDDSEETAVEPEATTTASTDEPAGESAMEEVD
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| BDBM34573 |
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| n/a |
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| Name | BDBM34573 |
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| Synonyms: | (1-oxidospiro[benzimidazol-1-ium-2,1'-cyclohexane]-5-yl)-phenyl-amine | 1-oxidanidyl-N-phenyl-spiro[benzimidazol-1-ium-2,1'-cyclohexane]-5-amine | 1-oxido-N-phenyl-5-spiro[benzimidazol-1-ium-2,1'-cyclohexane]amine | 1-oxido-N-phenylspiro[benzimidazol-1-ium-2,1'-cyclohexane]-5-amine | MLS000079671 | SMR000035951 | cid_657546 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19N3O |
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| Mol. Mass. | 293.363 |
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| SMILES | [O-][N+]1=c2ccc(Nc3ccccc3)cc2=NC11CCCCC1 |c:1,16| |
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| Structure | 
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