| Reaction Details |
|---|
 | Report a problem with these data |
| Target | ATP-dependent molecular chaperone HSP82 |
|---|
| Ligand | BDBM64932 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole |
|---|
| EC50 | 291±1285 nM |
|---|
| Citation |  PubChem, PC Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| ATP-dependent molecular chaperone HSP82 |
|---|
| Name: | ATP-dependent molecular chaperone HSP82 |
|---|
| Synonyms: | heat shock protein 90 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 80784.12 |
|---|
| Organism: | Candida albicans |
|---|
| Description: | gi_994798 |
|---|
| Residue: | 707 |
|---|
| Sequence: | MADAKVETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLE
SEPELFIRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTKSFMEALSAGADVSMI
GQFGVGFYSLFLVADHVQVISKHNDDEQYVWESNAGGKFTVTLDETNERLGRGTMLRLFL
KEDQLEYLEEKRIKEVVKKHSEFVAYPIQLVVTKEVEKEVPETEEEDKAAEEDDKKPKLE
EVKDEEDEKKEKKTKTVKEEVTETEELNKTKPLWTRNPSDITQDEYNAFYKSISNDWEDP
LAVKHFSVEGQLEFRAILFVPKRAPFDAFESKKKKNNIKLYVRRVFITDDAEELIPEWLS
FIKGVVDSEDLPLNLSREMLQQNKILKVIRKNIVKKMIETFNEISEDQEQFNQFYTAFSK
NIKLGIHEDAQNRQSLAKLLRFYSTKSSEEMTSLSDYVTRMPEHQKNIYYITGESIKAVE
KSPFLDALKAKNFEVLFMVDPIDEYAMTQLKEFEDKKLVDITKDFELEESDEEKAAREKE
IKEYEPLTKALKDILGDQVEKVVVSYKLVDAPAAIRTGQFGWSANMERIMKAQALRDTTM
SSYMSSKKTFEISPSSPIIKELKKKVETDGAEDKTVKDLTTLLFDTALLTSGFTLDEPSN
FAHRINRLIALGLNIDDDSEETAVEPEATTTASTDEPAGESAMEEVD
|
|
|
|---|
| BDBM64932 |
|---|
| n/a |
|---|
| Name | BDBM64932 |
|---|
| Synonyms: | 4-[benzyl(methyl)sulfamoyl]-N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)benzamide | 4-{[benzyl(methyl)amino]sulfonyl}-N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)benzamide | MLS000086352 | N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-[methyl-(phenylmethyl)sulfamoyl]benzamide | SMR000021854 | cid_2051214 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H20N4O4S |
|---|
| Mol. Mass. | 412.462 |
|---|
| SMILES | CN(Cc1ccccc1)S(=O)(=O)c1ccc(cc1)C(=O)Nc1nnc(o1)C1CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
