| Reaction Details |
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 | Report a problem with these data |
| Target | Inward rectifier potassium channel 2 |
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| Ligand | BDBM65867 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Confirmation dose response assay for compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1 |
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| IC50 | 37657±10796 nM |
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| Citation |  PubChem, PC Confirmation dose response assay for compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1 PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Inward rectifier potassium channel 2 |
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| Name: | Inward rectifier potassium channel 2 |
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| Synonyms: | Irk1 | KCNJ2_MOUSE | Kcnj2 | inward rectifier potassium channel 2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 48383.35 |
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| Organism: | Mus musculus |
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| Description: | gi_6680530 |
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| Residue: | 428 |
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| Sequence: | MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFIN
VGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDTSKVSK
ACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVM
AKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEG
EYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEG
MVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARD
LAEKKYILSNANSFCYENEVALTSKEEEEDSENGVPESTSTDSPPGIDLHNQASVPLEPR
PLRRESEI
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|
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| BDBM65867 |
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| n/a |
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| Name | BDBM65867 |
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| Synonyms: | (1-benzyl-4-piperidyl)-(4-chlorobenzyl)amine | 1-benzyl-N-(4-chlorobenzyl)-4-piperidinamine | 1-benzyl-N-[(4-chlorophenyl)methyl]piperidin-4-amine | MLS000974662 | N-[(4-chlorophenyl)methyl]-1-(phenylmethyl)-4-piperidinamine | N-[(4-chlorophenyl)methyl]-1-(phenylmethyl)piperidin-4-amine | SMR000496472 | cid_784405 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H23ClN2 |
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| Mol. Mass. | 314.852 |
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| SMILES | Clc1ccc(CNC2CCN(Cc3ccccc3)CC2)cc1 |
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| Structure | 
|
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