| Reaction Details |
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 | Report a problem with these data |
| Target | Inward rectifier potassium channel 2 |
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| Ligand | BDBM65872 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Confirmation dose response assay for compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1 |
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| IC50 | 24626±18083 nM |
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| Citation |  PubChem, PC Confirmation dose response assay for compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1 PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Inward rectifier potassium channel 2 |
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| Name: | Inward rectifier potassium channel 2 |
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| Synonyms: | Irk1 | KCNJ2_MOUSE | Kcnj2 | inward rectifier potassium channel 2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 48383.35 |
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| Organism: | Mus musculus |
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| Description: | gi_6680530 |
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| Residue: | 428 |
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| Sequence: | MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFIN
VGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDTSKVSK
ACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVM
AKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEG
EYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEG
MVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARD
LAEKKYILSNANSFCYENEVALTSKEEEEDSENGVPESTSTDSPPGIDLHNQASVPLEPR
PLRRESEI
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| BDBM65872 |
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| n/a |
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| Name | BDBM65872 |
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| Synonyms: | 1-[(4-fluorobenzyl)amino]-3-(4-methylphenoxy)propan-2-ol | 1-[(4-fluorophenyl)methylamino]-3-(4-methylphenoxy)-2-propanol | 1-[(4-fluorophenyl)methylamino]-3-(4-methylphenoxy)propan-2-ol | MLS001175430 | SMR000590574 | cid_4213523 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H20FNO2 |
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| Mol. Mass. | 289.3446 |
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| SMILES | Cc1ccc(OCC(O)CNCc2ccc(F)cc2)cc1 |
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| Structure | 
|
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