BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
Target60S ribosomal protein L19-A
LigandBDBM203
Substrate/Competitorn/a
Meas. Tech.Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50 5053±n/a nM
Citation PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
60S ribosomal protein L19-A
Name:60S ribosomal protein L19-A
Synonyms:RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:Enzyme Catalytic Domain
Mol. Mass.:21739.62
Organism:Saccharomyces cerevisiae
Description:gi_536029
Residue:189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSK
SRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLY
HVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEK
RDALLKEDA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM203
n/a
NameBDBM203
Synonyms:2-(4-fluorophenyl)-4-quinolinecarboxylic acid [2-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]-2-oxoethyl] ester | 2-(4-fluorophenyl)cinchoninic acid [2-[4-(2-furoyl)piperazino]-2-keto-ethyl] ester | AC1M5QV8 | AKOS002484993 | KUC105874N | MLS000098972 | MLS000879917 | Oprea1_088030 | SMR000060977 | T0505-6328 | ZINC03215799 | [2-[4-(furan-2-carbonyl)piperazin-1-yl]-2-oxoethyl] 2-(4-fluorophenyl)quinoline-4-carboxylate | [2-[4-(furan-2-ylcarbonyl)piperazin-1-yl]-2-oxidanylidene-ethyl] 2-(4-fluorophenyl)quinoline-4-carboxylate | cid_2334417 | ksc-8-129-6
TypeSmall organic molecule
Emp. Form.C27H22FN3O5
Mol. Mass.487.4791
SMILESFc1ccc(cc1)-c1cc(C(=O)OCC(=O)N2CCN(CC2)C(=O)c2ccco2)c2ccccc2n1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: