| Reaction Details |
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 | Report a problem with these data |
| Target | 60S ribosomal protein L19-A |
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| Ligand | BDBM65988 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits |
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| EC50 | 980±n/a nM |
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| Citation |  PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| 60S ribosomal protein L19-A |
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| Name: | 60S ribosomal protein L19-A |
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| Synonyms: | RL19A_YEAST | RPL19A | RPL23A | YL14A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 21739.62 |
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| Organism: | Saccharomyces cerevisiae |
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| Description: | gi_536029 |
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| Residue: | 189 |
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| Sequence: | MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSK
SRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLY
HVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEK
RDALLKEDA
|
|
|
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| BDBM65988 |
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| n/a |
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| Name | BDBM65988 |
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| Synonyms: | 1-(tert-butyl)-3-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | 1-tert-butyl-3-(4-fluorophenyl)-4-pyrazolo[3,4-d]pyrimidinamine | 1-tert-butyl-3-(4-fluorophenyl)pyrazolo[3,4-d]pyrimidin-4-amine | MLS000326584 | SMR000179224 | [1-tert-butyl-3-(4-fluorophenyl)pyrazolo[3,4-d]pyrimidin-4-yl]amine | cid_1489656 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H16FN5 |
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| Mol. Mass. | 285.3194 |
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| SMILES | CC(C)(C)n1nc(-c2ccc(F)cc2)c2c(N)ncnc12 |
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| Structure | 
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