| Reaction Details |
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 | Report a problem with these data |
| Target | Vacuolar aminopeptidase 1 |
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| Ligand | BDBM43506 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits |
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| EC50 | >33000±n/a nM |
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| Citation |  PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Vacuolar aminopeptidase 1 |
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| Name: | Vacuolar aminopeptidase 1 |
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| Synonyms: | AMPL_YEAST | APE1 | API | LAP4 | YSC1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 57084.90 |
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| Organism: | Saccharomyces cerevisiae |
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| Description: | gi_486173 |
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| Residue: | 514 |
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| Sequence: | MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFI
YKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNW
RAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLL
YKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNE
PPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAP
RLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVER
SSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHM
ATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHS
IRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL
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| BDBM43506 |
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| n/a |
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| Name | BDBM43506 |
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| Synonyms: | 3-[4-phenyl-6-(trifluoromethyl)pyrimidin-2-yl]sulfonylpropionic acid ethyl ester | 3-[[4-phenyl-6-(trifluoromethyl)-2-pyrimidinyl]sulfonyl]propanoic acid ethyl ester | MLS000051020 | SMR000078801 | cid_2219262 | ethyl 3-[4-phenyl-6-(trifluoromethyl)pyrimidin-2-yl]sulfonylpropanoate | ethyl 3-{[4-phenyl-6-(trifluoromethyl)-2-pyrimidinyl]sulfonyl}propanoate |
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| Type | Small organic molecule |
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| Emp. Form. | C16H15F3N2O4S |
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| Mol. Mass. | 388.362 |
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| SMILES | CCOC(=O)CCS(=O)(=O)c1nc(cc(n1)C(F)(F)F)-c1ccccc1 |
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| Structure | 
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