| Reaction Details |
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 | Report a problem with these data |
| Target | Vacuolar aminopeptidase 1 |
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| Ligand | BDBM65052 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits |
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| EC50 | 7771±n/a nM |
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| Citation |  PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Vacuolar aminopeptidase 1 |
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| Name: | Vacuolar aminopeptidase 1 |
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| Synonyms: | AMPL_YEAST | APE1 | API | LAP4 | YSC1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 57084.90 |
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| Organism: | Saccharomyces cerevisiae |
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| Description: | gi_486173 |
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| Residue: | 514 |
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| Sequence: | MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFI
YKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNW
RAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLL
YKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNE
PPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAP
RLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVER
SSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHM
ATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHS
IRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL
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| BDBM65052 |
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| n/a |
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| Name | BDBM65052 |
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| Synonyms: | 3,4-dihydro-2H-quinolin-1-yl-[5-(3,4-dihydro-2H-quinolin-1-ylcarbonyl)thiophen-2-yl]methanone | 3,4-dihydro-2H-quinolin-1-yl-[5-[3,4-dihydro-2H-quinolin-1-yl(oxo)methyl]-2-thiophenyl]methanone | MLS000564123 | SMR000151637 | [5-(3,4-dihydro-2H-quinoline-1-carbonyl)-2-thienyl]-(3,4-dihydro-2H-quinolin-1-yl)methanone | [5-(3,4-dihydro-2H-quinoline-1-carbonyl)thiophen-2-yl]-(3,4-dihydro-2H-quinolin-1-yl)methanone | cid_2314002 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H22N2O2S |
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| Mol. Mass. | 402.509 |
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| SMILES | O=C(N1CCCc2ccccc12)c1ccc(s1)C(=O)N1CCCc2ccccc12 |
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| Structure | 
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