Ki Summary

Reaction Details

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Target

Photoreceptor-specific nuclear receptor

Ligand

BDBM59833

Substrate/Competitor

n/a

Meas. Tech.

TR-FRET-based biochemical high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3)

IC50

1492±n/a nM

Citation

PubChem, PC TR-FRET-based biochemical high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Photoreceptor-specific nuclear receptor

Name:

Photoreceptor-specific nuclear receptor

Synonyms:

NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor

Type:

PROTEIN

Mol. Mass.:

44699.83

Organism:

Homo sapiens (Human)

Description:

ChEMBL_401901

Residue:

410

Sequence:

METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYG
IYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQN
ERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITA
ETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPV
FSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMET
RVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAH
HPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN

BDBM59833

n/a

Name

BDBM59833

Synonyms:

2-(8-chloro-4-keto-2-thioxo-1H-benzofuro[3,2-d]pyrimidin-3-yl)acetic acid ethyl ester | 2-(8-chloro-4-oxo-2-sulfanylidene-1H-benzofuro[3,2-d]pyrimidin-3-yl)acetic acid ethyl ester | MLS000519963 | SMR000130378 | cid_9551120 | ethyl 2-(8-chloranyl-4-oxidanylidene-2-sulfanylidene-1H-[1]benzofuro[3,2-d]pyrimidin-3-yl)ethanoate | ethyl 2-(8-chloro-4-oxo-2-sulfanylidene-1H-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetate

Type

Small organic molecule

Emp. Form.

C14H11ClN2O4S

Mol. Mass.

338.766

SMILES

CCOC(=O)Cn1c(=S)[nH]c2c3cc(Cl)ccc3oc2c1=O

Structure