Ki Summary

Reaction Details

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Target

Photoreceptor-specific nuclear receptor

Ligand

BDBM41042

Substrate/Competitor

n/a

Meas. Tech.

TR-FRET-based biochemical high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3)

IC50

177.87±n/a nM

Citation

PubChem, PC TR-FRET-based biochemical high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Photoreceptor-specific nuclear receptor

Name:

Photoreceptor-specific nuclear receptor

Synonyms:

NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor

Type:

PROTEIN

Mol. Mass.:

44699.83

Organism:

Homo sapiens (Human)

Description:

ChEMBL_401901

Residue:

410

Sequence:

METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYG
IYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQN
ERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITA
ETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPV
FSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMET
RVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAH
HPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN

BDBM41042

n/a

Name

BDBM41042

Synonyms:

7-(4-fluorophenyl)-5-(4-methylphenyl)-4-pyrido[2,3-d]pyrimidinamine | 7-(4-fluorophenyl)-5-(4-methylphenyl)pyrido[2,3-d]pyrimidin-4-amine | 7-(4-fluorophenyl)-5-(4-methylphenyl)pyrido[2,3-d]pyrimidin-4-ylamine | MLS000538794 | SMR000161339 | [7-(4-fluorophenyl)-5-(p-tolyl)pyrido[2,3-d]pyrimidin-4-yl]amine | cid_1234281

Type

Small organic molecule

Emp. Form.

C20H15FN4

Mol. Mass.

330.3583

SMILES

Cc1ccc(cc1)-c1cc(nc2ncnc(N)c12)-c1ccc(F)cc1

Structure