| Reaction Details |
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 | Report a problem with these data |
| Target | Isoform 2 of Nuclear receptor corepressor 2 (TRAC-1) |
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| Ligand | BDBM66173 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) |
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| IC50 | 1297±n/a nM |
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| Citation |  PubChem, PC Counterscreen for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3): TR-FRET-based biochemical high throughput dose response assay to identify agonists of the interaction between peroxisome proliferator-activated receptor gamma (PPARg) and nuclear receptor co-repressor 2 (NCOR2) PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Isoform 2 of Nuclear receptor corepressor 2 (TRAC-1) |
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| Name: | Isoform 2 of Nuclear receptor corepressor 2 (TRAC-1) |
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| Synonyms: | CTG26 | NCOR2 | NCOR2_HUMAN | Nuclear receptor corepressor 2 (TRAC-1) | nuclear receptor corepressor 2 isoform 2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 81401.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9Y618-2 gi_116256445 |
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| Residue: | 766 |
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| Sequence: | MAQRADMLRGLSPRESSLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLP
TAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVE
HAPIWRPGTEQSSGSSGGGGGSSSRPASHSHAHQHSPISPRTQDALQQRPSVLHNTGMKG
IITAVEPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRV
ARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPH
HASPDPPAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLT
HDKGLPKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPG
VKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYL
PPPDHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLL
YRDGEQTEPSRMGSKSPGNTSQPPAFFSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYN
ISQPGTEIFNMPAITGTGLMTYRSQAVQEHASTNMGLEAIIRKALMGGGGKAKVSGRPSS
RKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWEDRPSSAGSTPFPYNPLIMRL
QAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLLCSQYETLSDSE
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| BDBM66173 |
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| n/a |
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| Name | BDBM66173 |
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| Synonyms: | MLS000666816 | N-(5-bromanylpyridin-2-yl)-2-[2-[(2,6-dimethylphenyl)amino]-2-oxidanylidene-ethoxy]benzamide | N-(5-bromo-2-pyridinyl)-2-[2-(2,6-dimethylanilino)-2-oxoethoxy]benzamide | N-(5-bromo-2-pyridinyl)-2-{2-[(2,6-dimethylphenyl)amino]-2-oxoethoxy}benzamide | N-(5-bromo-2-pyridyl)-2-[2-(2,6-dimethylanilino)-2-keto-ethoxy]benzamide | N-(5-bromopyridin-2-yl)-2-[2-(2,6-dimethylanilino)-2-oxoethoxy]benzamide | SMR000271402 | cid_1329083 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20BrN3O3 |
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| Mol. Mass. | 454.317 |
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| SMILES | Cc1cccc(C)c1NC(=O)COc1ccccc1C(=O)Nc1ccc(Br)cn1 |
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| Structure | 
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