| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Isoform 2 of Nuclear receptor corepressor 2 (TRAC-1) |
|---|
| Ligand | BDBM47284 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Counterscreen for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) |
|---|
| IC50 | 1390±n/a nM |
|---|
| Citation |  PubChem, PC Counterscreen for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3): TR-FRET-based biochemical high throughput dose response assay to identify agonists of the interaction between peroxisome proliferator-activated receptor gamma (PPARg) and nuclear receptor co-repressor 2 (NCOR2) PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Isoform 2 of Nuclear receptor corepressor 2 (TRAC-1) |
|---|
| Name: | Isoform 2 of Nuclear receptor corepressor 2 (TRAC-1) |
|---|
| Synonyms: | CTG26 | NCOR2 | NCOR2_HUMAN | Nuclear receptor corepressor 2 (TRAC-1) | nuclear receptor corepressor 2 isoform 2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 81401.89 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9Y618-2 gi_116256445 |
|---|
| Residue: | 766 |
|---|
| Sequence: | MAQRADMLRGLSPRESSLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLP
TAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVE
HAPIWRPGTEQSSGSSGGGGGSSSRPASHSHAHQHSPISPRTQDALQQRPSVLHNTGMKG
IITAVEPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRV
ARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPH
HASPDPPAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLT
HDKGLPKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPG
VKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYL
PPPDHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLL
YRDGEQTEPSRMGSKSPGNTSQPPAFFSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYN
ISQPGTEIFNMPAITGTGLMTYRSQAVQEHASTNMGLEAIIRKALMGGGGKAKVSGRPSS
RKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWEDRPSSAGSTPFPYNPLIMRL
QAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLLCSQYETLSDSE
|
|
|
|---|
| BDBM47284 |
|---|
| n/a |
|---|
| Name | BDBM47284 |
|---|
| Synonyms: | 2-chloranyl-3-oxidanyl-benzo[c]chromen-6-one | 2-chloro-3-hydroxy-6-benzo[c][1]benzopyranone | 2-chloro-3-hydroxy-6H-benzo[c]chromen-6-one | 2-chloro-3-hydroxy-benzo[c]chromen-6-one | 2-chloro-3-hydroxybenzo[c]chromen-6-one | MLS000690352 | SMR000300153 | cid_5428505 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H7ClO3 |
|---|
| Mol. Mass. | 246.646 |
|---|
| SMILES | Oc1cc2oc(=O)c3ccccc3c2cc1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
