| Reaction Details |
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 | Report a problem with these data |
| Target | Guanine nucleotide-binding protein G(o) subunit alpha |
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| Ligand | BDBM67699 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao with additional round of SAR compounds. |
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| EC50 | >30000±0 nM |
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| Citation |  PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao with additional round of SAR compounds. PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Guanine nucleotide-binding protein G(o) subunit alpha |
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| Name: | Guanine nucleotide-binding protein G(o) subunit alpha |
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| Synonyms: | GNAO1 | GNAO_HUMAN | Guanine nucleotide-binding protein G(o), alpha subunit 1 | guanine nucleotide-binding protein G(o) subunit alpha isoform a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40043.59 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_321106 |
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| Residue: | 354 |
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| Sequence: | MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG
FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF
SAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRV
KTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDET
TNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDA
AAYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY
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| BDBM67699 |
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| n/a |
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| Name | BDBM67699 |
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| Synonyms: | (3-chloranyl-6-nitro-1-benzothiophen-2-yl)-piperazin-1-yl-methanone | (3-chloro-6-nitro-1-benzothiophen-2-yl)-(1-piperazinyl)methanone | (3-chloro-6-nitro-1-benzothiophen-2-yl)-piperazin-1-ylmethanone | (3-chloro-6-nitro-benzothiophen-2-yl)-piperazino-methanone | KSC-1-99c | KUC103872N | cid_4496360 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H12ClN3O3S |
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| Mol. Mass. | 325.771 |
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| SMILES | [O-][N+](=O)c1ccc2c(Cl)c(sc2c1)C(=O)N1CCNCC1 |
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| Structure | 
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