Reaction Details |
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Target | DNA damage-inducible transcript 3 protein |
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Ligand | BDBM39024 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress |
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IC50 | <160±n/a nM |
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Citation | PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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DNA damage-inducible transcript 3 protein |
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Name: | DNA damage-inducible transcript 3 protein |
Synonyms: | Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 19175.17 |
Organism: | Mus musculus |
Description: | gi_160707929 |
Residue: | 168 |
Sequence: | MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
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BDBM39024 |
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n/a |
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Name | BDBM39024 |
Synonyms: | 3-[(2-chloro-4-methylol-phenoxy)methyl]benzoic acid | 3-[[2-chloranyl-4-(hydroxymethyl)phenoxy]methyl]benzoic acid | 3-[[2-chloro-4-(hydroxymethyl)phenoxy]methyl]benzoic acid | 3-{[2-chloro-4-(hydroxymethyl)phenoxy]methyl}benzoic acid | MLS000099276 | SMR000073537 | cid_893460 |
Type | Small organic molecule |
Emp. Form. | C15H13ClO4 |
Mol. Mass. | 292.714 |
SMILES | OCc1ccc(OCc2cccc(c2)C(O)=O)c(Cl)c1 |
Structure |
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