Reaction Details |
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Target | DNA damage-inducible transcript 3 protein |
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Ligand | BDBM68010 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress |
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IC50 | <160±n/a nM |
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Citation | PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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DNA damage-inducible transcript 3 protein |
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Name: | DNA damage-inducible transcript 3 protein |
Synonyms: | Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 19175.17 |
Organism: | Mus musculus |
Description: | gi_160707929 |
Residue: | 168 |
Sequence: | MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
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BDBM68010 |
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n/a |
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Name | BDBM68010 |
Synonyms: | (2Z,6E)-4-tert-butyl-2,6-bis(2-furanylmethylidene)-1-cyclohexanone | (2Z,6E)-4-tert-butyl-2,6-bis(2-furfurylidene)cyclohexanone | (2Z,6E)-4-tert-butyl-2,6-bis(2-furylmethylene)cyclohexanone | (2Z,6E)-4-tert-butyl-2,6-bis(furan-2-ylmethylidene)cyclohexan-1-one | MLS000580624 | SMR000204787 | cid_12004979 |
Type | Small organic molecule |
Emp. Form. | C20H22O3 |
Mol. Mass. | 310.3869 |
SMILES | CC(C)(C)C1C\C(=C\c2ccco2)C(=O)\C(C1)=C\c1ccco1 |
Structure |
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