| Reaction Details |
|---|
 | Report a problem with these data |
| Target | DNA damage-inducible transcript 3 protein |
|---|
| Ligand | BDBM64626 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress |
|---|
| IC50 | <160±n/a nM |
|---|
| Citation |  PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| DNA damage-inducible transcript 3 protein |
|---|
| Name: | DNA damage-inducible transcript 3 protein |
|---|
| Synonyms: | Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 19175.17 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | gi_160707929 |
|---|
| Residue: | 168 |
|---|
| Sequence: | MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
|
|
|
|---|
| BDBM64626 |
|---|
| n/a |
|---|
| Name | BDBM64626 |
|---|
| Synonyms: | 2-Chloro-N-[2,2,2-trifluoro-1-(6-nitro-benzothiazol-2-ylamino)-1-trifluoromethyl-ethyl]-benzamide | 2-chloranyl-N-[1,1,1,3,3,3-hexakis(fluoranyl)-2-[(6-nitro-1,3-benzothiazol-2-yl)amino]propan-2-yl]benzamide | 2-chloro-N-[1,1,1,3,3,3-hexafluoro-2-[(6-nitro-1,3-benzothiazol-2-yl)amino]propan-2-yl]benzamide | 2-chloro-N-[2,2,2-trifluoro-1-[(6-nitro-1,3-benzothiazol-2-yl)amino]-1-(trifluoromethyl)ethyl]benzamide | MLS000592113 | SMR000218320 | cid_1716838 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H9ClF6N4O3S |
|---|
| Mol. Mass. | 498.787 |
|---|
| SMILES | [O-][N+](=O)c1ccc2nc(NC(NC(=O)c3ccccc3Cl)(C(F)(F)F)C(F)(F)F)sc2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
