| Reaction Details |
|---|
 | Report a problem with these data |
| Target | DNA damage-inducible transcript 3 protein |
|---|
| Ligand | BDBM61541 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress |
|---|
| IC50 | <160±n/a nM |
|---|
| Citation |  PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| DNA damage-inducible transcript 3 protein |
|---|
| Name: | DNA damage-inducible transcript 3 protein |
|---|
| Synonyms: | Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 19175.17 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | gi_160707929 |
|---|
| Residue: | 168 |
|---|
| Sequence: | MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
|
|
|
|---|
| BDBM61541 |
|---|
| n/a |
|---|
| Name | BDBM61541 |
|---|
| Synonyms: | (Z)-2,3-bis(chloranyl)-3-[(2-chlorophenyl)methylsulfinyl]-N-(6-methoxypyridin-3-yl)prop-2-enamide | (Z)-2,3-dichloro-3-(2-chlorobenzyl)sulfinyl-N-(6-methoxy-3-pyridyl)acrylamide | (Z)-2,3-dichloro-3-[(2-chlorophenyl)methylsulfinyl]-N-(6-methoxy-3-pyridinyl)-2-propenamide | (Z)-2,3-dichloro-3-[(2-chlorophenyl)methylsulfinyl]-N-(6-methoxypyridin-3-yl)prop-2-enamide | 2,3-dichloro-3-[(2-chlorobenzyl)sulfinyl]-N-(6-methoxy-3-pyridinyl)acrylamide | MLS000706839 | SMR000334342 | cid_1475345 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H13Cl3N2O3S |
|---|
| Mol. Mass. | 419.71 |
|---|
| SMILES | COc1ccc(NC(=O)C(Cl)=C(Cl)S(=O)Cc2ccccc2Cl)cn1 |w:11.11| |
|---|
| Structure | 
|
|---|
Search and Browse
