Reaction Details |
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Target | DNA damage-inducible transcript 3 protein |
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Ligand | BDBM63866 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress |
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IC50 | <160±n/a nM |
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Citation | PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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DNA damage-inducible transcript 3 protein |
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Name: | DNA damage-inducible transcript 3 protein |
Synonyms: | Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 19175.17 |
Organism: | Mus musculus |
Description: | gi_160707929 |
Residue: | 168 |
Sequence: | MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
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BDBM63866 |
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n/a |
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Name | BDBM63866 |
Synonyms: | Bruceolide | MLS000728513 | SMR000445627 | cid_16745524 |
Type | Small organic molecule |
Emp. Form. | C21H26O10 |
Mol. Mass. | 438.4251 |
SMILES | [H][C@]12[C@@H](O)C(=O)O[C@]3([H])C[C@@]4([H])C(C)=C(O)C(=O)C[C@@]4(C)C4C(O)[C@H](O)[C@@]1(OC[C@@]234)C(=O)OC |t:13| |
Structure |
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