Ki Summary

Reaction Details

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Target

Krueppel-like factor 5

Ligand

BDBM70193

Substrate/Competitor

n/a

Meas. Tech.

Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1)

IC50

>39841±n/a nM

Citation

PubChem, PC Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Krueppel-like factor 5

Name:

Krueppel-like factor 5

Synonyms:

Type:

Enzyme Catalytic Domain

Mol. Mass.:

50808.71

Organism:

Homo sapiens (Human)

Description:

Q13887

Residue:

457

Sequence:

MATRVLSMSARLGPVPQPPAPQDEPVFAQLKPVLGAANPARDAALFPGEELKHAHHRPQA
QPAPAQAPQPAQPPATGPRLPPEDLVQTRCEMEKYLTPQLPPVPIIPEHKKYRRDSASVV
DQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIFSHQSETTAPPP
APTQALPEFTSIFSSHQTAAPEVNNIFIKQELPTPDLHLSVPTQQGHLYQLLNTPDLDMP
SSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPPCTYTMPSQFLPQQATYF
PPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVRYN
RRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDEL
TRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN

BDBM70193

n/a

Name

BDBM70193

Synonyms:

N-(5,5-dimethyl-7-oxidanylidene-4,6-dihydro-1,3-benzothiazol-2-yl)-1,3-benzothiazole-6-carboxamide | N-(5,5-dimethyl-7-oxo-4,6-dihydro-1,3-benzothiazol-2-yl)-1,3-benzothiazole-6-carboxamide | N-(7-keto-5,5-dimethyl-4,6-dihydro-1,3-benzothiazol-2-yl)-1,3-benzothiazole-6-carboxamide | SR-01000006927 | SR-01000006927-3 | cid_4437203

Type

Small organic molecule

Emp. Form.

C17H15N3O2S2

Mol. Mass.

357.45

SMILES

CC1(C)Cc2nc(NC(=O)c3ccc4ncsc4c3)sc2C(=O)C1

Structure