Ki Summary

Reaction Details

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Target

Krueppel-like factor 5

Ligand

BDBM70199

Substrate/Competitor

n/a

Meas. Tech.

Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1)

IC50

>39841±n/a nM

Citation

PubChem, PC Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Krueppel-like factor 5

Name:

Krueppel-like factor 5

Synonyms:

Type:

Enzyme Catalytic Domain

Mol. Mass.:

50808.71

Organism:

Homo sapiens (Human)

Description:

Q13887

Residue:

457

Sequence:

MATRVLSMSARLGPVPQPPAPQDEPVFAQLKPVLGAANPARDAALFPGEELKHAHHRPQA
QPAPAQAPQPAQPPATGPRLPPEDLVQTRCEMEKYLTPQLPPVPIIPEHKKYRRDSASVV
DQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIFSHQSETTAPPP
APTQALPEFTSIFSSHQTAAPEVNNIFIKQELPTPDLHLSVPTQQGHLYQLLNTPDLDMP
SSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPPCTYTMPSQFLPQQATYF
PPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVRYN
RRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDEL
TRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN

BDBM70199

n/a

Name

BDBM70199

Synonyms:

2-(3,4-dimethylphenoxy)-N-[2-[3-(trifluoromethyl)phenyl]-5-benzotriazolyl]acetamide | 2-(3,4-dimethylphenoxy)-N-[2-[3-(trifluoromethyl)phenyl]benzotriazol-5-yl]acetamide | 2-(3,4-dimethylphenoxy)-N-[2-[3-(trifluoromethyl)phenyl]benzotriazol-5-yl]ethanamide | SR-01000528153 | SR-01000528153-2 | cid_1114257

Type

Small organic molecule

Emp. Form.

C23H19F3N4O2

Mol. Mass.

440.4178

SMILES

Cc1ccc(OCC(=O)Nc2ccc3nn(nc3c2)-c2cccc(c2)C(F)(F)F)cc1C

Structure