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TargetKruppel-like factor 5
LigandBDBM70201
Substrate/Competitorn/a
Meas. Tech.Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1)
IC50 4556±n/a nM
Citation PubChem PC Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1) PubChem Bioassay (2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Kruppel-like factor 5
Name:Kruppel-like factor 5
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:50808.71
Organism:Homo sapiens (Human)
Description:Q13887
Residue:457
Sequence:
MATRVLSMSARLGPVPQPPAPQDEPVFAQLKPVLGAANPARDAALFPGEELKHAHHRPQA
QPAPAQAPQPAQPPATGPRLPPEDLVQTRCEMEKYLTPQLPPVPIIPEHKKYRRDSASVV
DQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIFSHQSETTAPPP
APTQALPEFTSIFSSHQTAAPEVNNIFIKQELPTPDLHLSVPTQQGHLYQLLNTPDLDMP
SSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPPCTYTMPSQFLPQQATYF
PPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVRYN
RRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDEL
TRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM70201
n/a
NameBDBM70201
Synonyms:N-[2-(4-fluorophenyl)-5-benzotriazolyl]-2,2-dimethylpropanamide | N-[2-(4-fluorophenyl)benzotriazol-5-yl]-2,2-dimethyl-propanamide | N-[2-(4-fluorophenyl)benzotriazol-5-yl]-2,2-dimethyl-propionamide | N-[2-(4-fluorophenyl)benzotriazol-5-yl]-2,2-dimethylpropanamide | SR-03000001317 | SR-03000001317-1 | cid_17027240
TypeSmall organic molecule
Emp. Form.C17H17FN4O
Mol. Mass.312.3415
SMILESCC(C)(C)C(=O)Nc1ccc2nn(nc2c1)-c1ccc(F)cc1
Structure
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