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TargetKruppel-like factor 5
LigandBDBM70209
Substrate/Competitorn/a
Meas. Tech.Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1)
IC50>39841±n/a nM
Citation PubChem PC Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1) PubChem Bioassay (2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Kruppel-like factor 5
Name:Kruppel-like factor 5
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:50808.71
Organism:Homo sapiens (Human)
Description:Q13887
Residue:457
Sequence:
MATRVLSMSARLGPVPQPPAPQDEPVFAQLKPVLGAANPARDAALFPGEELKHAHHRPQA
QPAPAQAPQPAQPPATGPRLPPEDLVQTRCEMEKYLTPQLPPVPIIPEHKKYRRDSASVV
DQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIFSHQSETTAPPP
APTQALPEFTSIFSSHQTAAPEVNNIFIKQELPTPDLHLSVPTQQGHLYQLLNTPDLDMP
SSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPPCTYTMPSQFLPQQATYF
PPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVRYN
RRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDEL
TRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM70209
n/a
NameBDBM70209
Synonyms:N-(5-acetyl-4-phenyl-1,3-thiazol-2-yl)-1,3-benzothiazole-6-carboxamide | N-(5-acetyl-4-phenyl-2-thiazolyl)-1,3-benzothiazole-6-carboxamide | N-(5-acetyl-4-phenyl-thiazol-2-yl)-1,3-benzothiazole-6-carboxamide | N-(5-ethanoyl-4-phenyl-1,3-thiazol-2-yl)-1,3-benzothiazole-6-carboxamide | SR-03000001326 | SR-03000001326-1 | cid_5048062
TypeSmall organic molecule
Emp. Form.C19H13N3O2S2
Mol. Mass.379.455
SMILESCC(=O)c1sc(NC(=O)c2ccc3ncsc3c2)nc1-c1ccccc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: