Ki Summary

Reaction Details

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Target

Krueppel-like factor 5

Ligand

BDBM70223

Substrate/Competitor

n/a

Meas. Tech.

Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1)

IC50

42616±n/a nM

Citation

PubChem, PC Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Krueppel-like factor 5

Name:

Krueppel-like factor 5

Synonyms:

Type:

Enzyme Catalytic Domain

Mol. Mass.:

50808.71

Organism:

Homo sapiens (Human)

Description:

Q13887

Residue:

457

Sequence:

MATRVLSMSARLGPVPQPPAPQDEPVFAQLKPVLGAANPARDAALFPGEELKHAHHRPQA
QPAPAQAPQPAQPPATGPRLPPEDLVQTRCEMEKYLTPQLPPVPIIPEHKKYRRDSASVV
DQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIFSHQSETTAPPP
APTQALPEFTSIFSSHQTAAPEVNNIFIKQELPTPDLHLSVPTQQGHLYQLLNTPDLDMP
SSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPPCTYTMPSQFLPQQATYF
PPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVRYN
RRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDEL
TRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN

BDBM70223

n/a

Name

BDBM70223

Synonyms:

N-(6-chloranyl-2-phenyl-benzotriazol-5-yl)cyclopropanecarboxamide | N-(6-chloro-2-phenyl-5-benzotriazolyl)cyclopropanecarboxamide | N-(6-chloro-2-phenyl-benzotriazol-5-yl)cyclopropanecarboxamide | N-(6-chloro-2-phenylbenzotriazol-5-yl)cyclopropanecarboxamide | SR-03000001353 | SR-03000001353-1 | cid_45281180

Type

Small organic molecule

Emp. Form.

C16H13ClN4O

Mol. Mass.

312.754

SMILES

Clc1cc2nn(nc2cc1NC(=O)C1CC1)-c1ccccc1

Structure