Ki Summary

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Target

Krueppel-like factor 5

Ligand

BDBM70224

Substrate/Competitor

n/a

Meas. Tech.

Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1)

IC50

>39841±n/a nM

Citation

PubChem, PC Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Krueppel-like factor 5

Name:

Krueppel-like factor 5

Synonyms:

Type:

Enzyme Catalytic Domain

Mol. Mass.:

50808.71

Organism:

Homo sapiens (Human)

Description:

Q13887

Residue:

457

Sequence:

MATRVLSMSARLGPVPQPPAPQDEPVFAQLKPVLGAANPARDAALFPGEELKHAHHRPQA
QPAPAQAPQPAQPPATGPRLPPEDLVQTRCEMEKYLTPQLPPVPIIPEHKKYRRDSASVV
DQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIFSHQSETTAPPP
APTQALPEFTSIFSSHQTAAPEVNNIFIKQELPTPDLHLSVPTQQGHLYQLLNTPDLDMP
SSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPPCTYTMPSQFLPQQATYF
PPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVRYN
RRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDEL
TRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN

BDBM70224

n/a

Name

BDBM70224

Synonyms:

N-(6-chloranyl-2-phenyl-benzotriazol-5-yl)-3,4-dihydro-2H-chromene-3-carboxamide | N-(6-chloro-2-phenyl-5-benzotriazolyl)-3,4-dihydro-2H-1-benzopyran-3-carboxamide | N-(6-chloro-2-phenyl-benzotriazol-5-yl)chroman-3-carboxamide | N-(6-chloro-2-phenylbenzotriazol-5-yl)-3,4-dihydro-2H-chromene-3-carboxamide | SR-03000001355 | SR-03000001355-1 | cid_45281184

Type

Small organic molecule

Emp. Form.

C22H17ClN4O2

Mol. Mass.

404.849

SMILES

Clc1cc2nn(nc2cc1NC(=O)C1COc2ccccc2C1)-c1ccccc1

Structure