| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome b-245 heavy chain |
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| Ligand | BDBM42323 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Late stage results from the probe development effort to identify inhibitors of (NADPH oxidase 1) NOX1: Family selectivity: Set 2 |
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| IC50 | 5000±n/a nM |
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| Citation |  PubChem, PC Late stage results from the probe development effort to identify inhibitors of (NADPH oxidase 1) NOX1: Family selectivity: Set 2 PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Cytochrome b-245 heavy chain |
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| Name: | Cytochrome b-245 heavy chain |
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| Synonyms: | CGD91-phox | CY24B_HUMAN | CYBB | Cytochrome b(558) subunit beta | Cytochrome b-245, beta polypeptide [Homo sapiens] | Cytochrome b558 subunit beta | Heme-binding membrane glycoprotein gp91phox | NADPH oxidase 2 | NADPH oxidase 2 (NOX2) | NOX2 | Neutrophil cytochrome b 91 kDa polypeptide | Superoxide-generating NADPH oxidase heavy chain subunit | gp91-1 | gp91-phox | p22 phagocyte B-cytochrome |
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| Type: | Enzyme |
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| Mol. Mass.: | 65355.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P04839 |
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| Residue: | 570 |
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| Sequence: | MGNWAVNEGLSIFVILVWLGLNVFLFVWYYRVYDIPPKFFYTRKLLGSALALARAPAACL
NFNCMLILLPVCRNLLSFLRGSSACCSTRVRRQLDRNLTFHKMVAWMIALHSAIHTIAHL
FNVEWCVNARVNNSDPYSVALSELGDRQNESYLNFARKRIKNPEGGLYLAVTLLAGITGV
VITLCLILIITSSTKTIRRSYFEVFWYTHHLFVIFFIGLAIHGAERIVRGQTAESLAVHN
ITVCEQKISEWGKIKECPIPQFAGNPPMTWKWIVGPMFLYLCERLVRFWRSQQKVVITKV
VTHPFKTIELQMKKKGFKMEVGQYIFVKCPKVSKLEWHPFTLTSAPEEDFFSIHIRIVGD
WTEGLFNACGCDKQEFQDAWKLPKIAVDGPFGTASEDVFSYEVVMLVGAGIGVTPFASIL
KSVWYKYCNNATNLKLKKIYFYWLCRDTHAFEWFADLLQLLESQMQERNNAGFLSYNIYL
TGWDESQANHFAVHHDEEKDVITGLKQKTLYGRPNWDNEFKTIASQHPNTRIGVFLCGPE
ALAETLSKQSISNSESGPRGVHFIFNKENF
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| BDBM42323 |
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| n/a |
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| Name | BDBM42323 |
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| Synonyms: | 1-(10H-phenothiazin-2-yl)ethanone | MLS000047624 | SMR000033635 | cid_81131 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H11NOS |
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| Mol. Mass. | 241.308 |
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| SMILES | CC(=O)c1ccc2Sc3ccccc3Nc2c1 |
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| Structure | 
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