| Reaction Details |
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 | Report a problem with these data |
| Target | Protein LANA1 |
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| Ligand | BDBM74291 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Polarization Cell-Free Homogeneous Dose Retest to Confirm Inhibitors of the LANA Histone H2A/H2B Interaction |
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| EC50 | >75000±n/a nM |
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| Citation |  PubChem, PC Fluorescence Polarization Cell-Free Homogeneous Dose Retest to Confirm Inhibitors of the LANA Histone H2A/H2B Interaction PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Protein LANA1 |
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| Name: | Protein LANA1 |
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| Synonyms: | LANA | LANA1 | LANA1_HHV8P |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 131093.36 |
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| Organism: | Human herpesvirus 8 |
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| Description: | Q9QR71 |
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| Residue: | 1129 |
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| Sequence: | MAPPGMRLRSGRSTGAPLTRGSCRKRNRSPERCDLGDDLHLQPRRKHVADSVDGRECGPH
TLPIPGSPTVFTSGLPAFVSSPTLPVAPIPSPAPATPLPPPALLPPVTTSSSPIPPSHPV
SPGTTDTHSPSPALPPTQSPESSQRPPLSSPTGRPDSSTPMRPPPSQQTTPPHSPTTPPP
EPPSKSSPDSLAPSTLRSLRKRRLSSPQGPSTLNPICQSPPVSPPRCDFANRSVYPPWAT
ESPIYVGSSSDGDTPPRQPPTSPISIGSSSPSEGSWGDDTAMLVLLAEIAEEASKNEKEC
SENNQAGEDNGDNEISKESQVDKDDNDNKDDEEEQETDEEDEEDDEEDDEEDDEEDDEED
DEEDDEEDDEEEDEEEDEEEDEEEDEEEEEDEEDDDDEDNEDEEDDEEEDKKEDEEDGGD
GNKTLSIQSSQQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQREPQQRE
PQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQQEPQQQE
PQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQDEQQQD
EQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQEQQDEQQQDEQQQQDEQEQQEEQEQQEE
QQQDEQQQDEQQQDEQQQDEQEQQDEQQQDEQQQQDEQEQQEEQEQQEEQEQQEEQEQQE
EQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQ
ELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQEQELEEVEEQEQEQEEQE
LEEVEEQEQEQEEQEEQELEEVEEQEEQELEEVEEQEEQELEEVEEQEQQGVEQQEQETV
EEPIILHGSSSEDEMEVDYPVVSTHEQIASSPPGDNTPDDDPQPGPSREYRYVLRTSPPH
RPGVRMRRVPVTHPKKPHPRYQQPPVPYRQIDDCPAKARPQHIFYRRFLGKDGRRDPKCQ
WKFAVIFWGNDPYGLKKLSQAFQFGGVKAGPVSCLPHPGPDQSPITYCVYVYCQNKDTSK
KVQMARLAWEASHPLAGNLQSSIVKFKKPLPLTQPGENQGPGDSPQEMT
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| BDBM74291 |
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| n/a |
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| Name | BDBM74291 |
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| Synonyms: | 4-(4-morpholinyl)-4-oxo-N-[[3-(trifluoromethyl)phenyl]methyl]butanamide | 4-keto-4-morpholino-N-[3-(trifluoromethyl)benzyl]butyramide | 4-morpholin-4-yl-4-oxidanylidene-N-[[3-(trifluoromethyl)phenyl]methyl]butanamide | 4-morpholin-4-yl-4-oxo-N-[[3-(trifluoromethyl)phenyl]methyl]butanamide | MLS002181636 | SMR001270666 | cid_25162200 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H19F3N2O3 |
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| Mol. Mass. | 344.3289 |
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| SMILES | FC(F)(F)c1cccc(CNC(=O)CCC(=O)N2CCOCC2)c1 |
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| Structure | 
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