| Reaction Details |
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 | Report a problem with these data |
| Target | Protein LANA1 |
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| Ligand | BDBM74295 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Polarization Cell-Free Homogeneous Dose Retest to Confirm Inhibitors of the LANA Histone H2A/H2B Interaction |
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| EC50 | >75000±n/a nM |
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| Citation |  PubChem, PC Fluorescence Polarization Cell-Free Homogeneous Dose Retest to Confirm Inhibitors of the LANA Histone H2A/H2B Interaction PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Protein LANA1 |
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| Name: | Protein LANA1 |
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| Synonyms: | LANA | LANA1 | LANA1_HHV8P |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 131093.36 |
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| Organism: | Human herpesvirus 8 |
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| Description: | Q9QR71 |
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| Residue: | 1129 |
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| Sequence: | MAPPGMRLRSGRSTGAPLTRGSCRKRNRSPERCDLGDDLHLQPRRKHVADSVDGRECGPH
TLPIPGSPTVFTSGLPAFVSSPTLPVAPIPSPAPATPLPPPALLPPVTTSSSPIPPSHPV
SPGTTDTHSPSPALPPTQSPESSQRPPLSSPTGRPDSSTPMRPPPSQQTTPPHSPTTPPP
EPPSKSSPDSLAPSTLRSLRKRRLSSPQGPSTLNPICQSPPVSPPRCDFANRSVYPPWAT
ESPIYVGSSSDGDTPPRQPPTSPISIGSSSPSEGSWGDDTAMLVLLAEIAEEASKNEKEC
SENNQAGEDNGDNEISKESQVDKDDNDNKDDEEEQETDEEDEEDDEEDDEEDDEEDDEED
DEEDDEEDDEEEDEEEDEEEDEEEDEEEEEDEEDDDDEDNEDEEDDEEEDKKEDEEDGGD
GNKTLSIQSSQQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQREPQQRE
PQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQQEPQQQE
PQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQDEQQQD
EQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQEQQDEQQQDEQQQQDEQEQQEEQEQQEE
QQQDEQQQDEQQQDEQQQDEQEQQDEQQQDEQQQQDEQEQQEEQEQQEEQEQQEEQEQQE
EQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQ
ELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQEQELEEVEEQEQEQEEQE
LEEVEEQEQEQEEQEEQELEEVEEQEEQELEEVEEQEEQELEEVEEQEQQGVEQQEQETV
EEPIILHGSSSEDEMEVDYPVVSTHEQIASSPPGDNTPDDDPQPGPSREYRYVLRTSPPH
RPGVRMRRVPVTHPKKPHPRYQQPPVPYRQIDDCPAKARPQHIFYRRFLGKDGRRDPKCQ
WKFAVIFWGNDPYGLKKLSQAFQFGGVKAGPVSCLPHPGPDQSPITYCVYVYCQNKDTSK
KVQMARLAWEASHPLAGNLQSSIVKFKKPLPLTQPGENQGPGDSPQEMT
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| BDBM74295 |
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| n/a |
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| Name | BDBM74295 |
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| Synonyms: | MLS002180901 | N-(6-amino-1-isobutyl-2,4-diketo-pyrimidin-5-yl)-4-(1,3-benzothiazol-2-yl)-N-butyl-butyramide | N-[6-amino-1-(2-methylpropyl)-2,4-dioxo-5-pyrimidinyl]-4-(1,3-benzothiazol-2-yl)-N-butylbutanamide | N-[6-amino-1-(2-methylpropyl)-2,4-dioxopyrimidin-5-yl]-4-(1,3-benzothiazol-2-yl)-N-butylbutanamide | N-[6-azanyl-1-(2-methylpropyl)-2,4-bis(oxidanylidene)pyrimidin-5-yl]-4-(1,3-benzothiazol-2-yl)-N-butyl-butanamide | SMR001269931 | cid_25162304 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H31N5O3S |
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| Mol. Mass. | 457.589 |
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| SMILES | CCCCN(C(=O)CCCc1nc2ccccc2s1)c1c(N)n(CC(C)C)c(=O)[nH]c1=O |
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| Structure | 
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