Reaction Details |
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Target | Tyrosine-protein phosphatase non-receptor type 7 |
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Ligand | BDBM74450 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 |
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IC50 | >79400±0 nM |
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Citation | PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Tyrosine-protein phosphatase non-receptor type 7 |
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Name: | Tyrosine-protein phosphatase non-receptor type 7 |
Synonyms: | He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP) |
Type: | Protein |
Mol. Mass.: | 40530.79 |
Organism: | Homo sapiens (Human) |
Description: | P35236 |
Residue: | 360 |
Sequence: | MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
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BDBM74450 |
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n/a |
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Name | BDBM74450 |
Synonyms: | 3-[2-(2,3,5,6-tetrafluoro-4-methylol-anilino)ethylamino]cyclohex-2-en-1-one | 3-[2-[2,3,5,6-tetrafluoro-4-(hydroxymethyl)anilino]ethylamino]-1-cyclohex-2-enone | 3-[2-[2,3,5,6-tetrafluoro-4-(hydroxymethyl)anilino]ethylamino]cyclohex-2-en-1-one | 3-[2-[[2,3,5,6-tetrakis(fluoranyl)-4-(hydroxymethyl)phenyl]amino]ethylamino]cyclohex-2-en-1-one | MLS000039349 | SMR000041400 | cid_660485 |
Type | Small organic molecule |
Emp. Form. | C15H16F4N2O2 |
Mol. Mass. | 332.2934 |
SMILES | OCc1c(F)c(F)c(NCCNC2=CC(=O)CCC2)c(F)c1F |t:12| |
Structure |
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