| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 7 |
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| Ligand | BDBM46244 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis of compounds that inhibit HePTP - Set 2 |
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| IC50 | 651±n/a nM |
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| Citation |  PubChem, PC SAR analysis of compounds that inhibit HePTP - Set 2 PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Tyrosine-protein phosphatase non-receptor type 7 |
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| Name: | Tyrosine-protein phosphatase non-receptor type 7 |
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| Synonyms: | He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP) |
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| Type: | Protein |
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| Mol. Mass.: | 40530.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35236 |
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| Residue: | 360 |
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| Sequence: | MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
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| BDBM46244 |
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| n/a |
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| Name | BDBM46244 |
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| Synonyms: | 3-[[(E)-3-[4-(4-chlorobenzyl)oxyphenyl]-2-cyano-acryloyl]amino]benzoic acid | 3-[[(E)-3-[4-[(4-chlorophenyl)methoxy]phenyl]-2-cyano-1-oxoprop-2-enyl]amino]benzoic acid | 3-[[(E)-3-[4-[(4-chlorophenyl)methoxy]phenyl]-2-cyano-prop-2-enoyl]amino]benzoic acid | 3-[[(E)-3-[4-[(4-chlorophenyl)methoxy]phenyl]-2-cyanoprop-2-enoyl]amino]benzoic acid | MLS-0334991.0001 | cid_1516220 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H17ClN2O4 |
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| Mol. Mass. | 432.856 |
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| SMILES | OC(=O)c1cccc(NC(=O)C(=C\c2ccc(OCc3ccc(Cl)cc3)cc2)\C#N)c1 |
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| Structure | 
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