| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 7 |
|---|
| Ligand | BDBM65974 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | SAR analysis of compounds that inhibit HePTP - Set 2 |
|---|
| IC50 | 394±n/a nM |
|---|
| Citation |  PubChem, PC SAR analysis of compounds that inhibit HePTP - Set 2 PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Tyrosine-protein phosphatase non-receptor type 7 |
|---|
| Name: | Tyrosine-protein phosphatase non-receptor type 7 |
|---|
| Synonyms: | He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 40530.79 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35236 |
|---|
| Residue: | 360 |
|---|
| Sequence: | MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
|
|
|
|---|
| BDBM65974 |
|---|
| n/a |
|---|
| Name | BDBM65974 |
|---|
| Synonyms: | 3-[(5E)-5-[4-(4-chlorobenzyl)oxy-3-methoxy-benzylidene]-4-keto-2-thioxo-thiazolidin-3-yl]benzoic acid | 3-[(5E)-5-[[4-[(4-chlorophenyl)methoxy]-3-methoxy-phenyl]methylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]benzoic acid | 3-[(5E)-5-[[4-[(4-chlorophenyl)methoxy]-3-methoxyphenyl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]benzoic acid | 3-[(5E)-5-[[4-[(4-chlorophenyl)methoxy]-3-methoxyphenyl]methylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]benzoic acid | MLS-0435625.0001 | cid_16466007 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H18ClNO5S2 |
|---|
| Mol. Mass. | 511.997 |
|---|
| SMILES | COc1cc(\C=C2\SC(=S)N(C2=O)c2cccc(c2)C(O)=O)ccc1OCc1ccc(Cl)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
