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TargetTyrosine-protein phosphatase non-receptor type 7
LigandBDBM34347
Substrate/Competitorn/a
Meas. Tech.SAR analysis of compounds that inhibit HePTP - Set 2
IC50 8470±n/a nM
Citation PubChem, PC SAR analysis of compounds that inhibit HePTP - Set 2 PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Tyrosine-protein phosphatase non-receptor type 7
Name:Tyrosine-protein phosphatase non-receptor type 7
Synonyms:He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:Protein
Mol. Mass.:40530.79
Organism:Homo sapiens (Human)
Description:P35236
Residue:360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
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  Blast E-value cutoff:
BDBM34347
n/a
NameBDBM34347
Synonyms:MLS000056753 | SMR000066372 | [4-amino-3-(3-methylphenyl)-2-sulfanylidene-1,3-thiazol-5-yl]-(4-methylpiperazin-1-yl)methanone | [4-amino-3-(3-methylphenyl)-2-sulfanylidene-5-thiazolyl]-(4-methyl-1-piperazinyl)methanone | [4-amino-3-(m-tolyl)-2-thioxo-4-thiazolin-5-yl]-(4-methylpiperazino)methanone | [4-azanyl-3-(3-methylphenyl)-2-sulfanylidene-1,3-thiazol-5-yl]-(4-methylpiperazin-1-yl)methanone | cid_3000187
TypeSmall organic molecule
Emp. Form.C16H20N4OS2
Mol. Mass.348.486
SMILESCN1CCN(CC1)C(=O)c1sc(=S)n(c1N)-c1cccc(C)c1
Structure
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