Reaction Details |
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Target | Tyrosine-protein phosphatase non-receptor type 7 |
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Ligand | BDBM34347 |
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Substrate/Competitor | n/a |
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Meas. Tech. | SAR analysis of compounds that inhibit HePTP - Set 2 |
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IC50 | 8470±n/a nM |
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Citation | PubChem, PC SAR analysis of compounds that inhibit HePTP - Set 2 PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Tyrosine-protein phosphatase non-receptor type 7 |
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Name: | Tyrosine-protein phosphatase non-receptor type 7 |
Synonyms: | He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP) |
Type: | Protein |
Mol. Mass.: | 40530.79 |
Organism: | Homo sapiens (Human) |
Description: | P35236 |
Residue: | 360 |
Sequence: | MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEP
ICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHA
SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFW
EMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQY
QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGC
FIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
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BDBM34347 |
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n/a |
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Name | BDBM34347 |
Synonyms: | MLS000056753 | SMR000066372 | [4-amino-3-(3-methylphenyl)-2-sulfanylidene-1,3-thiazol-5-yl]-(4-methylpiperazin-1-yl)methanone | [4-amino-3-(3-methylphenyl)-2-sulfanylidene-5-thiazolyl]-(4-methyl-1-piperazinyl)methanone | [4-amino-3-(m-tolyl)-2-thioxo-4-thiazolin-5-yl]-(4-methylpiperazino)methanone | [4-azanyl-3-(3-methylphenyl)-2-sulfanylidene-1,3-thiazol-5-yl]-(4-methylpiperazin-1-yl)methanone | cid_3000187 |
Type | Small organic molecule |
Emp. Form. | C16H20N4OS2 |
Mol. Mass. | 348.486 |
SMILES | CN1CCN(CC1)C(=O)c1sc(=S)n(c1N)-c1cccc(C)c1 |
Structure |
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