| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase |
|---|
| Ligand | BDBM50210 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response concentration confirmation of uHTS hits from a small molecule activators of human intestinal alkaline phosphatase via a luminescent assay |
|---|
| EC50 | 8300±n/a nM |
|---|
| Citation |  PubChem, PC Dose Response concentration confirmation of uHTS hits from a small molecule activators of human intestinal alkaline phosphatase via a luminescent assay PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Intestinal-type alkaline phosphatase |
|---|
| Name: | Intestinal-type alkaline phosphatase |
|---|
| Synonyms: | ALPI | Alkaline phosphatase, intestinal | Intestinal alkaline phosphatase | PPBI_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 56804.94 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1278525 |
|---|
| Residue: | 528 |
|---|
| Sequence: | MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLG
DGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLC
GVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYA
HTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADA
SQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRD
PTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERA
GQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVF
NSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHV
MAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP
|
|
|
|---|
| BDBM50210 |
|---|
| n/a |
|---|
| Name | BDBM50210 |
|---|
| Synonyms: | 4-Methyl-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylic acid (2,4-dihydroxy-benzylidene)-hydrazide | 4-methyl-5-oxidanylidene-N'-[(E)-(2-oxidanyl-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)methyl]-1,4-dihydropyrazole-3-carbohydrazide | MLS000553611 | N'-[(E)-(2-hydroxy-4-keto-cyclohexa-2,5-dien-1-ylidene)methyl]-5-keto-4-methyl-2-pyrazoline-3-carbohydrazide | N'-[(E)-(2-hydroxy-4-oxo-1-cyclohexa-2,5-dienylidene)methyl]-4-methyl-5-oxo-1,4-dihydropyrazole-3-carbohydrazide | N'-[(E)-(2-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-4-methyl-5-oxo-1,4-dihydropyrazole-3-carbohydrazide | SMR000171667 | cid_5759606 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H12N4O4 |
|---|
| Mol. Mass. | 276.2481 |
|---|
| SMILES | Cc1c([nH][nH]c1=O)C(=O)NN=Cc1ccc(O)cc1O |w:10.10| |
|---|
| Structure | 
|
|---|
Search and Browse
